A procurement manager from a pharmaceutical company in Shenzhen once called me and said, 'I need HEPA filters for my cleanroom'. When I asked which grade, he said, 'Just HEPA, the usual kind.' The problem is, there is no 'usual kind' of HEPA — there are at least seven distinct grades under international standards, ranging from 99.95% to 99.999995% efficiency, and the difference between them can determine whether your cleanroom passes an EU GMP audit or fails.